Of course, as with anything, the lower the dose of delta-8 you take while the drug is active in your body, the lower the risk of an interaction. Effect of repeated administration of 11-hydroxy-delta 8-tetrahydrocannabinol, an active metabolite of delta 8-tetrahydrocannabinol, on the enzymatic system that metabolizes liver microsomal drugs in mice. Delta-9-tetrahydrocannabinol (THC) and cannabidiol are pharmacologically active cannabinoids in marijuana that are metabolized in cytochrome P450 (CYP), 3A4; THC is also metabolized by CYP2C9, a liver enzyme. The Delta-8 is a degraded delta-9, has a lot in common with its older sister compound and is simply a softer version.
Alcohol is also known to cause interactions with many medications, so if you're taking delta-8 with a doctor's prescription, avoid drinking until the next day. The natural amount of delta-8 THC in hemp is very low and additional chemicals are needed to convert other hemp cannabinoids, such as CBD, into delta-8 THC (that is, obviously, the first thing you should do is ask your doctor about the possibility of an interaction). Delta-8 tetrahydrocannabinol, also known as delta-8 THC, is a psychoactive substance found in the Cannabis sativa plant, of which marijuana and hemp are two varieties. We mentioned earlier that CYP3A4 is a metabolite needed to break down these drugs in the system.
It's important for consumers to know that delta-8 THC products have not been evaluated or approved by the FDA for safe use in any context. Delta-8 THC is one of more than 100 cannabinoids naturally produced by the cannabis plant, but it is not found in significant quantities in the cannabis plant. Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels after weight loss. In addition, the FDA is concerned about the proliferation of products that contain delta-8 THC and that are marketed for therapeutic or medical purposes, even if they have not been approved by the FDA.
The FDA is aware of the growing concern surrounding the delta-8 THC products currently being sold online and in stores. Although more research is needed, marijuana can have serious interactions with drugs such as warfarin (increased international standard quotient and risk of bleeding); clobazam (higher risk of benzodiazepine toxicity); central nervous system depressants and sympathomimetics (additive effects); and theophylline, clozapine and olanzapine (reduced efficacy). The FDA is also concerned that delta-8 THC products may expose consumers to much higher levels of the substance than those found naturally in raw hemp and cannabis extracts.
